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Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily A member 1' and Ligand = 'BDBM50318482'
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50318482((-)-menthol | CHEMBL470670 | MENTHOL | US11406649,...)
Affinity DataEC50:  2.84E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50318482((-)-menthol | CHEMBL470670 | MENTHOL | US11406649,...)
Affinity DataEC50:  9.60E+4nMAssay Description:Agonist activity at recombinant human TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for 5 mins by Fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTransient receptor potential cation channel subfamily A member 1(Mus musculus)
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50318482((-)-menthol | CHEMBL470670 | MENTHOL | US11406649,...)
Affinity DataEC50:  5.60E+4nMAssay Description:Antagonist activity at mouse TRPA1 channel expressed in CHO cells assessed as blockade of agonist-induced whole cell conductance by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed