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Found 2 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 3' and Ligand = 'BDBM190588'
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM190588(US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM190588(US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
In DepthDetails US Patent