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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tubulin' and Ligand = 'BDBM50044965'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50044965
PNG
(1-Methyl-2-phenyl-1H-quinolin-4-one | CHEMBL277048)
Show SMILES Cn1c(cc(=O)c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C16H13NO/c1-17-14-10-6-5-9-13(14)16(18)11-15(17)12-7-3-2-4-8-12/h2-11H,1H3
PDB
MMDB

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Article
PubMed
n/an/a>4.00E+4n/an/an/an/an/an/a



Institute of Pharmaceutical Chemistry

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 36: 1146-56 (1993)


Article DOI: 10.1021/jm00061a005
BindingDB Entry DOI: 10.7270/Q2BV7H8S
More data for this
Ligand-Target Pair
Tubulin


(Sus scrofa (Pig))
BDBM50044965
PNG
(1-Methyl-2-phenyl-1H-quinolin-4-one | CHEMBL277048)
Show SMILES Cn1c(cc(=O)c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C16H13NO/c1-17-14-10-6-5-9-13(14)16(18)11-15(17)12-7-3-2-4-8-12/h2-11H,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>4.00E+4n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.(ITP)


J Med Chem 44: 3932-6 (2001)


Article DOI: 10.1021/jm0101085
BindingDB Entry DOI: 10.7270/Q2PK0FFW
More data for this
Ligand-Target Pair