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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50003376'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Type-1 angiotensin II receptor


(Cavia porcellus)
BDBM50003376
PNG
(2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Show SMILES CCc1cc(OCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2c(cccc2n1)C#N
Show InChI InChI=1S/C26H20N6O/c1-2-20-14-24(25-19(15-27)6-5-9-23(25)28-20)33-16-17-10-12-18(13-11-17)21-7-3-4-8-22(21)26-29-31-32-30-26/h3-14H,2,16H2,1H3,(H,29,30,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparation


J Med Chem 35: 4027-38 (1992)


Article DOI: 10.1021/jm00100a007
BindingDB Entry DOI: 10.7270/Q2G44P8Q
More data for this
Ligand-Target Pair