BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-Protein Phosphatase (CD45)' and Ligand = 'BDBM50331945'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50331945
PNG
(Asp-BrPmp-Leu | CHEMBL1289231)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(cc1)C(Br)P(O)(O)=O)NC(=O)[C@@H](N)CC(O)=O)C(O)=O
Show InChI InChI=1S/C20H29BrN3O9P/c1-10(2)7-15(20(29)30)24-19(28)14(23-18(27)13(22)9-16(25)26)8-11-3-5-12(6-4-11)17(21)34(31,32)33/h3-6,10,13-15,17H,7-9,22H2,1-2H3,(H,23,27)(H,24,28)(H,25,26)(H,29,30)(H2,31,32,33)/t13-,14-,15-,17?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.60E+4n/an/an/an/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Inhibition of human CD45-cytoplasmic domain at 35 uM after 10 mins by Kitz-Wilson analysis


Bioorg Med Chem 18: 8679-86 (2010)


Article DOI: 10.1016/j.bmc.2010.09.040
BindingDB Entry DOI: 10.7270/Q2H995FP
More data for this
Ligand-Target Pair