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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM99534'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cephalon

US Patent
LigandPNGBDBM99534(CHEMBL2062805 | US8501936, 32)
Affinity DataIC50:  30.7nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cephalon

US Patent
LigandPNGBDBM99534(CHEMBL2062805 | US8501936, 32)
Affinity DataIC50:  31nMAssay Description:Inhibition of human JAK3 expressed in baculovirus using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed