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Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor UFO' and Ligand = 'BDBM300056'
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300056(N-(3-amino-3- methylbutan-2-yl)- 2-{[(2R)-1- metho...)
Affinity DataKi:  0.0340nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300056(N-(3-amino-3- methylbutan-2-yl)- 2-{[(2R)-1- metho...)
Affinity DataKi:  0.0880nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300056(N-(3-amino-3- methylbutan-2-yl)- 2-{[(2R)-1- metho...)
Affinity DataKi:  1.59nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300056(N-(3-amino-3- methylbutan-2-yl)- 2-{[(2R)-1- metho...)
Affinity DataKi:  2.80nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300056(N-(3-amino-3- methylbutan-2-yl)- 2-{[(2R)-1- metho...)
Affinity DataKi:  8.42nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent