Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 2' and Ligand = 'BDBM14245'
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14245(4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-car...)
Affinity DataKi:  320nM ΔG°:  -37.1kJ/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14245(4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-car...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human recombinant TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14245(4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-car...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed