Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
VEGF-receptor 2 and stem cell growth factor receptor (KDR and KIT) (Homo sapiens (human)) | BDBM50331023![]() ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of c-Kit after 30 mins by ELISA | J Med Chem 53: 8140-9 (2010) | |||||||||||
More data for this Ligand-Target Pair |