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Found 4 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50162157'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162157(1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162157(1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162157(1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162157(1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed