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Found 3 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50381698'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381698(CHEMBL1969102 | US8722890, 6)
Affinity DataIC50:  2nMAssay Description:Inhibition of KDR using 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381698(CHEMBL1969102 | US8722890, 6)
Affinity DataIC50:  2.18nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381698(CHEMBL1969102 | US8722890, 6)
Affinity DataIC50:  14nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed