BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM5885'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5885 (1-(3-methylphenyl)-3-[4-(1-oxo-2,3-dihydro-1H-isoi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...				Bioorg Med Chem Lett 14: 4505-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.041 BindingDB Entry DOI: 10.7270/Q2B27SH9
Abbott Laboratories					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM5885 (1-(3-methylphenyl)-3-[4-(1-oxo-2,3-dihydro-1H-isoi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...				Bioorg Med Chem Lett 14: 4505-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.041 BindingDB Entry DOI: 10.7270/Q2B27SH9
Abbott Laboratories					More data for this Ligand-Target Pair