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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor (V2)' and Ligand = 'BDBM50246645'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50246645
PNG
(1-(2-Methyl-4-(5-methyl-2,3,4,5-tetrahydro-1-benza...)
Show SMILES CC1CCCN(C(=O)c2ccc(CNC(=O)N3CCC[C@H]3C(=O)N(C)C)c(C)c2)c2ccccc12
Show InChI InChI=1S/C28H36N4O3/c1-19-9-7-15-31(24-11-6-5-10-23(19)24)26(33)21-13-14-22(20(2)17-21)18-29-28(35)32-16-8-12-25(32)27(34)30(3)4/h5-6,10-11,13-14,17,19,25H,7-9,12,15-16,18H2,1-4H3,(H,29,35)/t19?,25-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 220n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair