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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50229268'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1S


(Rattus norvegicus)
BDBM50229268
PNG
(CHEMBL306404)
Show SMILES CC(C)O\C(O)=C1\C(C(C#N)=C(C)N=C1C[S+]([O-])c1ccccc1)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C25H23F3N2O3S/c1-15(2)33-24(31)23-21(14-34(32)17-9-5-4-6-10-17)30-16(3)19(13-29)22(23)18-11-7-8-12-20(18)25(26,27)28/h4-12,15,22,31H,14H2,1-3H3/b24-23+
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine


J Med Chem 34: 2248-60 (1991)


Article DOI: 10.1021/jm00111a047
More data for this
Ligand-Target Pair