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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated potassium channel subunit Kv1.5' and Ligand = 'BDBM50306895'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50306895
PNG
((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1cccnc1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C23H21Cl2N5O/c1-14-21(23(31)29-11-3-5-19(29)16-4-2-9-26-13-16)22(30-20(28-14)8-10-27-30)15-6-7-17(24)18(25)12-15/h2,4,6-10,12-13,19,21-22H,3,5,11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human Kv1.5 channel expressed in mouse L929 cells


Bioorg Med Chem Lett 20: 1436-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.085
BindingDB Entry DOI: 10.7270/Q2MG7PM1
More data for this
Ligand-Target Pair