Found 2 Enz. Inhib. hit(s) with Target = 'Wee1-like protein kinase' and Ligand = 'BDBM50522511' TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research And Development
Curated by ChEMBL
Global Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research And Development
Curated by ChEMBL
Global Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 79nMAssay Description:Inhibition of WEE1 in human NCI-H1299 cells assessed as reduction in Cdc2 phosphorylation at Tyr15 residue measured after 6 hrs by ELISAMore data for this Ligand-Target Pair
