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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-Dependent Protein Kinase (PKA)' and Ligand = 'BDBM11826'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM11826
PNG
(Azepane Derivative 7 | N-((3R,4R)-4-{[4-(2-fluoro-...)
Show SMILES COc1ccc(O)c(C(=O)c2ccc(CN[C@@H]3CCCNC[C@H]3NC(=O)c3ccncc3)cc2)c1F
Show InChI InChI=1S/C27H29FN4O4/c1-36-23-9-8-22(33)24(25(23)28)26(34)18-6-4-17(5-7-18)15-31-20-3-2-12-30-16-21(20)32-27(35)19-10-13-29-14-11-19/h4-11,13-14,20-21,30-31,33H,2-3,12,15-16H2,1H3,(H,32,35)/t20-,21-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 800n/an/an/an/a7.222



Roche Diagnostics GmbH



Assay Description
In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...


J Med Chem 47: 1375-90 (2004)


Article DOI: 10.1021/jm0310479
BindingDB Entry DOI: 10.7270/Q2WM1BNX
More data for this
Ligand-Target Pair