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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-Dependent Protein Kinase (PKA)' and Ligand = 'BDBM2679'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM2679
PNG
(3,4-bis(2-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyr...)
Show SMILES Cc1[nH]c2ccccc2c1C1=C(C(=O)NC1=O)c1c(C)[nH]c2ccccc12
Show InChI InChI=1S/C22H17N3O2/c1-11-17(13-7-3-5-9-15(13)23-11)19-20(22(27)25-21(19)26)18-12(2)24-16-10-6-4-8-14(16)18/h3-10,23-24H,1-2H3,(H,25,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/a7.430



Laboratoires Glaxo



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Biol Chem 266: 15771-81 (1991)


Article DOI: 10.1021/jm0508282
BindingDB Entry DOI: 10.7270/Q2FF3QJ4
More data for this
Ligand-Target Pair