Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50042058'
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair