Found 12 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50346088'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant PDE4B by liquid scintillation counter methodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 288nMAssay Description:Inhibition of human Phosphodiesterase 4B from peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair