BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'p110α/p85α' and Ligand = 'BDBM207064'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
p110α/p85α


(Homo sapiens (Human))
BDBM207064
PNG
(US9260439, 41)
Show SMILES C[C@@H](O)C(=O)N1CC[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1
Show InChI InChI=1/C21H28N8O3/c1-13(30)19(31)28-4-2-15(12-28)29-5-3-16-17(14-10-23-20(22)24-11-14)25-21(26-18(16)29)27-6-8-32-9-7-27/h10-11,13,15,30H,2-9,12H2,1H3,(H2,22,23,24)/t13-,15+/s2
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
1.38n/an/an/an/an/an/an/an/a



Pfizer Inc

US Patent


Assay Description
PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...


US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair