BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'p110δ/p85α' and Ligand = 'BDBM189845'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
p110δ/p85α


(Homo sapiens (Human))
BDBM189845
PNG
(US9670194, Ex. 64 (S)-2-(1-((6-amino-5-(5-methyl-1...)
Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1
Show InChI InChI=1/C23H19ClN8O2/c1-12(28-20-18(19(25)26-11-27-20)22-31-30-13(2)34-22)21-29-16-10-6-9-15(24)17(16)23(33)32(21)14-7-4-3-5-8-14/h3-12H,1-2H3,(H3,25,26,27,28)/t12-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/a25



CALITOR SCIENCES, LLC

US Patent


Assay Description
PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...


US Patent US9670194 (2017)


BindingDB Entry DOI: 10.7270/Q2NS0S1D
More data for this
Ligand-Target Pair