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Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Monomerid = 10319
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10319((S)-(+)-5-{1-[2-(Thiophenoxymethyl)pyrrolidinyl]su...)
Affinity DataIC50:  44nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10319((S)-(+)-5-{1-[2-(Thiophenoxymethyl)pyrrolidinyl]su...)
Affinity DataIC50:  44nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed