Affinity DataKi: 270nMAssay Description:The activity of CK2α was tested using P81 filter isotopic assay, as it was described earlier [Łukowska-Chojnacka et al., Bioorg. Med. Chem....More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of CK2alpha in human PLC1 cells using (Arg)3(Glu)3Thr(Glu)3 as substrate after 24 hrs in presence of [32P]gammaGTPMore data for this Ligand-Target Pair
Affinity DataKi: 400nM ΔG°: -36.2kJ/mole IC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Binding affinity to CK2alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human CK2alpha using RRRDDDSDDD peptide substrate by P81 filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant GST-tagged CK-2 using RRRADDSDDDDD as substrate incubated for 5 mins by scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataKd: 790nMAssay Description:Binding affinity to recombinant human CK2alpha/beta expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair