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Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase 12' and Monomerid = 13123   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase 12


(Mus musculus)
BDBM13123
PNG
((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@@H](C(=O)NO)c1ccccc1
Show InChI InChI=1/C22H22N2O5S/c1-29-19-12-14-20(15-13-19)30(27,28)24(16-17-8-4-2-5-9-17)21(22(25)23-26)18-10-6-3-7-11-18/h2-15,21,26H,16H2,1H3,(H,23,25)/t21-/s2
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PC sid
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Similars

Article
PubMed
n/an/a 31n/an/an/an/an/an/a



Novartis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate


Bioorg Med Chem Lett 8: 897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00142-5
BindingDB Entry DOI: 10.7270/Q2NP24ZC
More data for this
Ligand-Target Pair