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Found 4 Enz. Inhib. hit(s) with Target = 'Lck' and Monomerid = 13219
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13219(2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13219(2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...)
Affinity DataIC50:  4.40E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13219(2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of mouse p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13219(2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,...)
Affinity DataIC50:  7.50E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed