BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 10A' and Monomerid = 14361

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

IC50: >1.60E+4nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [432-779](Homo sapiens (Human))
Plexxikon

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

IC50: 1.40E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed