Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Thrombin' and Monomerid = 16127
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  23nM ΔG°:  -43.2kJ/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  3.70E+3nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  4.15E+3nMAssay Description:Inhibition constant against bovine thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataKi:  4.15E+3nMAssay Description:Competitive reversible inhibition of bovine thrombin using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after 15 to 40 mins ...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair