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Found 4 Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 16152
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16152(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  10nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16152(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  10nMAssay Description:Inhibition of human uPA using S-2444 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16152(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  2.70E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16152(2-({4-chloro-1-[(diaminomethylidene)amino]isoquino...)
Affinity DataKi:  4.00E+4nMAssay Description:Ki values for compounds were calculated by incubation of each enzyme with its substrate and various compound concentrations. Absorbance was read at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed