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Found 7 Enz. Inhib. hit(s) with Target = 'Histamine H4 Receptor' and Monomerid = 22883
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in SK-NM-C cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  316nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  377nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed