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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 23918   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasminogen


(Homo sapiens (Human))
BDBM23918
PNG
(3-amidinophenylalanine deriv., 60 | 4-amino-N-(3-{...)
Show SMILES NCCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1
Show InChI InChI=1S/C27H39N7O4S/c28-12-3-8-25(35)32-22-6-2-7-23(18-22)39(37,38)33-24(17-20-4-1-5-21(16-20)26(30)31)27(36)34-14-10-19(9-13-29)11-15-34/h1-2,4-7,16,18-19,24,33H,3,8-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1
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Article
PubMed
2.50E+3n/an/an/an/an/an/an/an/a



Curacyte Chemistry GmbH



Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...


J Med Chem 49: 4116-26 (2006)


Article DOI: 10.1021/jm051272l
BindingDB Entry DOI: 10.7270/Q21C1V64
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM23918
PNG
(3-amidinophenylalanine deriv., 60 | 4-amino-N-(3-{...)
Show SMILES NCCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1
Show InChI InChI=1S/C27H39N7O4S/c28-12-3-8-25(35)32-22-6-2-7-23(18-22)39(37,38)33-24(17-20-4-1-5-21(16-20)26(30)31)27(36)34-14-10-19(9-13-29)11-15-34/h1-2,4-7,16,18-19,24,33H,3,8-15,17,28-29H2,(H3,30,31)(H,32,35)/t24-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
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B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.00E+3n/an/an/an/an/an/an/an/a



Curacyte Chemistry GmbH



Assay Description
The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...


J Med Chem 49: 4116-26 (2006)


Article DOI: 10.1021/jm051272l
BindingDB Entry DOI: 10.7270/Q21C1V64
More data for this
Ligand-Target Pair