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Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-Hydroxysteroid Dehydrogenase 1 (17-beta-HSD1)' and Monomerid = 25844   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
17-beta-Hydroxysteroid Dehydrogenase 1 (17-beta-HSD1)


(Homo sapiens (Human))
BDBM25844
PNG
(3-[1-(3-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]pheno...)
Show SMILES Oc1cccc(c1)-c1cn(nn1)-c1cccc(O)c1
Show InChI InChI=1S/C14H11N3O2/c18-12-5-1-3-10(7-12)14-9-17(16-15-14)11-4-2-6-13(19)8-11/h1-9,18-19H
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+3n/an/an/an/a7.037



Saarland University



Assay Description
Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...


J Med Chem 51: 6725-39 (2008)


Article DOI: 10.1021/jm8006917
BindingDB Entry DOI: 10.7270/Q2RB72XG
More data for this
Ligand-Target Pair