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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase LCK' and Monomerid = 26373
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM26373(4-methyl-3-N-(pyrimidin-5-yl)-1-N-[3-(trifluoromet...)
Affinity DataIC50:  239nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM26373(4-methyl-3-N-(pyrimidin-5-yl)-1-N-[3-(trifluoromet...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed