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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 29237   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM29237
PNG
(quinolinone, 8)
Show SMILES Fc1cccc2c(CN(C(=O)c3ccco3)c3ccccc3)cc(=O)[nH]c12
Show InChI InChI=1S/C21H15FN2O3/c22-17-9-4-8-16-14(12-19(25)23-20(16)17)13-24(15-6-2-1-3-7-15)21(26)18-10-5-11-27-18/h1-12H,13H2,(H,23,25)
PDB

GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/a25



Kalypsys Inc.



Assay Description
HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...


J Med Chem 52: 3047-62 (2009)


Article DOI: 10.1021/jm900173b
BindingDB Entry DOI: 10.7270/Q2D798RB
More data for this
Ligand-Target Pair