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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Src' and Monomerid = 3062   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Gallus gallus (Chicken))
BDBM3062
PNG
(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 29 | 6-(2,...)
Show SMILES CCN(CC)CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1
Show InChI InChI=1S/C21H25Cl2N5O/c1-4-28(5-2)11-7-10-24-21-25-13-14-12-15(20(29)27(3)19(14)26-21)18-16(22)8-6-9-17(18)23/h6,8-9,12-13H,4-5,7,10-11H2,1-3H3,(H,24,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 960n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of chicken c-Src tyrosine kinase


J Med Chem 41: 1752-63 (1998)


Article DOI: 10.1021/jm970634p
BindingDB Entry DOI: 10.7270/Q26T0KQ6
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM3062
PNG
(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 29 | 6-(2,...)
Show SMILES CCN(CC)CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1
Show InChI InChI=1S/C21H25Cl2N5O/c1-4-28(5-2)11-7-10-24-21-25-13-14-12-15(20(29)27(3)19(14)26-21)18-16(22)8-6-9-17(18)23/h6,8-9,12-13H,4-5,7,10-11H2,1-3H3,(H,24,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 960n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 41: 3276-92 (1998)


Article DOI: 10.1021/jm9802259
BindingDB Entry DOI: 10.7270/Q27P8WK3
More data for this
Ligand-Target Pair