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Found 3 Enz. Inhib. hit(s) with Target = 'ATP-Binding Cassette Transporter ABCG2' and Monomerid = 32617
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition assay using ABCG2 or BCRP1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition assay using ABCG2 or BCRP1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)
Affinity DataIC50:  3.34E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed