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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Src' and Monomerid = 4190   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM4190
PNG
(1,6-naphthyridin-2(1H)-one deriv. 7w | 4-[[3-(2,6-...)
Show SMILES CCN(CC)C(=O)c1ccc(Nc2cc3n(C)c(=O)c(cc3cn2)-c2c(Cl)cccc2Cl)cc1
Show InChI InChI=1S/C26H24Cl2N4O2/c1-4-32(5-2)25(33)16-9-11-18(12-10-16)30-23-14-22-17(15-29-23)13-19(26(34)31(22)3)24-20(27)7-6-8-21(24)28/h6-15H,4-5H2,1-3H3,(H,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 43: 3134-47 (2000)


Article DOI: 10.1021/jm000148t
BindingDB Entry DOI: 10.7270/Q2028PQ1
More data for this
Ligand-Target Pair