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Found 7 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50000857
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  150nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  500nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed