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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Purinergic receptor P2Y12' and Monomerid = 50000920   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purinergic receptor P2Y12


(Homo sapiens (Human))
BDBM50000920
PNG
(CHEMBL88218 | N-Cyclohexyl-4-(2-oxo-2,3-dihydro-1H...)
Show SMILES O=C(CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1)NC1CCCCC1
Show InChI InChI=1S/C20H24N4O3/c25-18(21-14-5-2-1-3-6-14)7-4-10-27-15-8-9-16-13(11-15)12-17-19(22-16)24-20(26)23-17/h8-9,11-12,14H,1-7,10H2,(H,21,25)(H2,22,23,24,26)
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Patents


Similars

Article
PubMed
n/an/an/an/a 40n/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)


J Med Chem 35: 2672-87 (1992)


Article DOI: 10.1021/jm00092a019
BindingDB Entry DOI: 10.7270/Q2513X52
More data for this
Ligand-Target Pair