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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50001169   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50001169
PNG
(2-benzo[d][1,3]thiazol-2-ylsulfanyl-1-ethanamino-N...)
Show SMILES CN(O)C(=O)NCCSc1nc2ccccc2s1
Show InChI InChI=1S/C11H13N3O2S2/c1-14(16)10(15)12-6-7-17-11-13-8-4-2-3-5-9(8)18-11/h2-5,16H,6-7H2,1H3,(H,12,15)
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 90n/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.


J Med Chem 35: 3180-3 (1992)


Article DOI: 10.1021/jm00095a012
BindingDB Entry DOI: 10.7270/Q2542P68
More data for this
Ligand-Target Pair