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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50002138   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50002138
PNG
(3,5-Dimethyl-8-piperazin-1-yl-imidazo[1,2-a]pyrazi...)
Show SMILES Cc1cnc2c(ncc(C)n12)N1CCNCC1
Show InChI InChI=1S/C12H17N5/c1-9-7-14-11(16-5-3-13-4-6-16)12-15-8-10(2)17(9)12/h7-8,13H,3-6H2,1-2H3
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
400n/an/an/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at Beta-1 adrenergic receptor in guinea pigs by [125I]CYP displacement


J Med Chem 35: 3845-57 (1992)


Article DOI: 10.1021/jm00099a012
BindingDB Entry DOI: 10.7270/Q2PZ59FX
More data for this
Ligand-Target Pair