Found 11 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Monomerid = 50003359
Affinity DataKi: 11nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]-4-DAMP from human muscarinic M4 receptor expressed in BHK-21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M4 expressed in A9 L cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 229nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.20nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Positive allosteric modulatory activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assess...More data for this Ligand-Target Pair
Affinity DataEC50: 186nMAssay Description:Agonist activity at human M4 receptor expressed in HEK293T cells by BRET based beta-arrestin engagement assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human M4 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.31E+3nMAssay Description:Agonist activity at human M4 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assessed as decrease in isopr...More data for this Ligand-Target Pair