Found 19 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Monomerid = 50006584 TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 600nMAssay Description:In vitro binding affinity for muscarinic M1 receptor by displacing [3H]-Pirenzepine binding on rat brain homogenate.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 1.95E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by liquid scintillation counterMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 1.95E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by microplate scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 1.95E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nMAssay Description:Binding affinity to Muscarinic acetylcholine receptor M1 by measuring its ability to displace [3H]pirenzepine from rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for inhibition of [3H]cis-methyldioxolane binding to label agonist sites (RCMD) in rat neocortexMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 955nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 955nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 955nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against human Muscarinic acetylcholine receptor M1 using [3H]-quinuclidinyl benzilate to label antagonist site (RQNB) in CHO cell...More data for this Ligand-Target Pair
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataIC50: 7.24E+3nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 3.50E+3nMAssay Description:Effective concentration for HMPA (human muscarinic inositol phosphate accumulation) activity measured in CHO cells expressing Muscarinic acetylcholin...More data for this Ligand-Target Pair
