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Found 7 Enz. Inhib. hit(s) with Target = 'Renin' and Monomerid = 50006844
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.320nMAssay Description:Inhibitory activity of the compound against renin was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.360nMAssay Description:In vitro inhibitory activity against monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.360nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.370nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in monkeyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  0.570nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  2nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in monkeyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50006844((S)-N-[(S)-2-(2-Amino-thiazol-4-yl)-1-((1S,2R,3S)-...)
Affinity DataIC50:  199nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed