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Found 5 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Monomerid = 50009291
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to muscarinic acetylcholine receptor was determined in presence of [3H]OXO-M radioligand (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to muscarinic acetylcholine receptor was determined in presence of [3H]QNB radioligand (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  22nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  8.79E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  8.79E+4nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article