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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50012791   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012791
PNG
(2,6-Di-tert-butyl-4-[2-(4-methoxy-phenyl)-vinyl]-p...)
Show SMILES COc1ccc(\C=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc1
Show InChI InChI=1S/C23H30O2/c1-22(2,3)19-14-17(15-20(21(19)24)23(4,5)6)9-8-16-10-12-18(25-7)13-11-16/h8-15,24H,1-7H3/b9-8+
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil 5-lipoxygenase


J Med Chem 33: 1892-8 (1990)


Article DOI: 10.1021/jm00169a010
BindingDB Entry DOI: 10.7270/Q2W95857
More data for this
Ligand-Target Pair