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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50014766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014766
PNG
(Bis-(4-chloro-phenyl)-pyrimidin-4-yl-methanol | CH...)
Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ccncn1
Show InChI InChI=1S/C17H12Cl2N2O/c18-14-5-1-12(2-6-14)17(22,16-9-10-20-11-21-16)13-3-7-15(19)8-4-13/h1-11,22H
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 322n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair