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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Monomerid = 50014812   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014812
PNG
(Bis-(4-chloro-phenyl)-(2H-[1,2,4]triazol-3-yl)-met...)
Show SMILES OC(c1nnc[nH]1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C15H11Cl2N3O/c16-12-5-1-10(2-6-12)15(21,14-18-9-19-20-14)11-3-7-13(17)8-4-11/h1-9,21H,(H,18,19,20)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>2.00E+3n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair