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Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50015406   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50015406
PNG
(4,6,7-Trimethyl-benzo[1,3]oxathiol-5-ol | CHEMBL27...)
Show SMILES Cc1c2OCSc2c(C)c(O)c1C
Show InChI InChI=1S/C10H12O2S/c1-5-6(2)9-10(13-4-12-9)7(3)8(5)11/h11H,4H2,1-3H3
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Sankyo Company Ltd.

Curated by ChEMBL


Assay Description
Evaluated for inhibition of the formation and release of 5-lipoxygenase in isolated guinea pig ileum


J Med Chem 33: 1491-6 (1990)


Article DOI: 10.1021/jm00167a032
BindingDB Entry DOI: 10.7270/Q2NG4PM6
More data for this
Ligand-Target Pair