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Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50016684   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50016684
PNG
(5-{[2-(4-Benzyloxy-phenyl)-acetyl]-hydroxy-amino}-...)
Show SMILES ON(CCCCC(O)=O)C(=O)Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H23NO5/c22-19(21(25)13-5-4-8-20(23)24)14-16-9-11-18(12-10-16)26-15-17-6-2-1-3-7-17/h1-3,6-7,9-12,25H,4-5,8,13-15H2,(H,23,24)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase


J Med Chem 32: 1836-42 (1989)


Article DOI: 10.1021/jm00128a027
BindingDB Entry DOI: 10.7270/Q2VT1R21
More data for this
Ligand-Target Pair